The increasing number of bowel cancer cases continues to attract attention, and the recent passing of James Van Der Beek has highlighted the seriousness of this illness once again.
Until recently, the causes of this increase were mostly unknown. However, new research is now pointing to an unexpected culprit.
Last week, we received the tragic news that actor James Van Der Beek had died. The star of Dawson’s Creek passed away at the young age of 48, with his family stating that he “faced his final days with courage, faith, and grace.”
In light of this, a GoFundMe campaign established to assist his wife, Kimberly, and their six children has already garnered over $2.6 million.
Beloved friends, such as Katie Holmes and Alfonso Ribeiro, have shared touching tributes to the actor, who learned he had bowel cancer after undergoing a colonoscopy in 2023.
Even though he was in “amazing shape” and led a “healthy” lifestyle, Van Der Beek noticed a “change in bowel habits” and initially suspected it might be due to his diet.

”I tried to eat healthy as much as I could, as far as I knew at the time. Though I’ve since learned a lot about what actually eating healthy is,” he told People in 2024.
For the Dawson’s Creek star, he had been open about his own symptoms.
“It was just a change in bowel habits,” he shared in this week’s cover story. “I thought, I probably need to change my diet a little bit. Maybe I need to stop coffee. Maybe I need to not put cream in the coffee. And then I finally took that out of my diet, and it didn’t improve, and I thought, all right, I better go get this checked out.”
Other warning signs of bowel cancer may include blood in your stools, abdominal discomfort, unexplained weight loss, severe fatigue, and unusual lumps in the stomach or rectal area. Experts advise anyone experiencing these symptoms to see their GP without delay.
When Van Der Beek disclosed that he had stage three colorectal cancer, the illness had already spread to nearby lymph nodes but had not reached distant areas of the body.
Surprising culprit
Sadly, James Van Der Beek did not overcome his illness, and his death has reignited conversations about the rising incidence of bowel cancer among younger individuals.
Some researchers contend that if this trend persists, the disease could potentially become the leading cause of cancer-related fatalities among young adults globally by 2030.
So, what’s causing this increase? The answer is complex, but studies are indicating a surprising factor: gut bacteria.
A recent study indicates that exposure during childhood or adolescence to a toxin produced by specific strains of E. coli, which thrive on highly processed diets, may lay the groundwork for aggressive colon cancer many years later.
An international team analyzed the complete DNA sequences of 981 colorectal tumors from patients in 11 different countries. They found notable geographic patterns in the mutations that contribute to cancer.
Two mutation signatures in particular, SBS88 and ID18, were especially significant due to their association with colibactin, a DNA-damaging toxin generated by certain E. coli strains. These bacterial “fingerprints” were found to be 3.3 times more prevalent in patients diagnosed before the age of 40 compared to those over 70.
Crucially, these mutations appear early in tumor development, indicating that the damage may occur years, even decades, prior to the official detection of cancer.
This discovery may help clarify why individuals under 50 are at the heart of one of the fastest-growing cancer epidemics of our era.
Important to remember one thing
Despite the concerning statistics, it’s vital to understand that early detection is key. Timely treatment can greatly enhance survival rates.
Nevertheless, many individuals hesitate to consult a doctor due to feelings of “embarrassment” or a desire to avoid causing a “fuss,” as noted by Dr. Jamie Murphy, a consultant colorectal surgeon.
“If detected in the early stages before spreading, nine out of ten cancers can be effectively treated,” he emphasizes. “Quick identification of bowel cancer truly saves lives.”
Dr. Murphy highlights that specific lifestyle choices can elevate the risk of developing bowel cancer.
“One significant factor is the increasing number of individuals living with obesity,” he states. “This condition can lead to chronic inflammation, insulin resistance, and alterations in gut bacteria, all of which may contribute to cancer development.”
Dietary habits are also influential.
“High consumption of processed foods, red meat, and low fiber diets are suspected to have an impact,” Dr. Murphy mentions, adding that a lack of physical activity can further heighten the risk. Conversely, “regular exercise is known to lower the risk of colorectal cancer by fostering healthy digestion and minimizing inflammation… so get active, everyone.”
Environmental elements might also play a role.
“Exposure to environmental toxins and pollutants… can disturb hormonal balance and harm cellular DNA, potentially leading to cancer,” Dr. Murphy clarifies. “Increased contact with these toxins through food, water, and air could represent a significant risk factor.”

The untimely death of James Van Der Beek serves as a poignant reminder of the harsh reality of bowel cancer. Although his passing is profoundly sad, we can take solace in the hope that his story raises awareness about this growing concern, encouraging early detection and ongoing research.
May his legacy propel advancements in comprehending why this illness is becoming more prevalent among younger adults — ultimately leading to lives being saved before it’s too late.